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为了解决常规双酚A检测分析方法无选择性、需要标准样品、预处理过程复杂等缺陷，以磁性石墨烯（MG）为基底、ZnO作为Zn源在MG表面原位生长ZIF-7，合成了高效导电复合膜MG@ZIF-7；选择MG@ZIF-7为载体、内分泌干扰物双酚A(BPA)为模板分子、丙烯酰为功能单体、二乙烯基苯为交联剂，采用表面分子印迹技术成功制备了分子印迹杂化膜（MG@ZIF7-MIP），并通过TEM、XRD、XPS、FT-IR等测试手段对其进行了分析表征；构建了以MG@ZIF7-MIP修饰电极为工作电极的分子印迹电化学传感器，对水环境中内分泌干扰物BPA进行选择性检测。结果表明：MG@ZIF7-MIP修饰电极对BPA的线性响应范围为0.001～0.100μmol/L(R=0.976 3)，响应平衡时间为4 min，检测限为9.84 ng/L(S/N=3)，建立了一种快速响应、实用性强、高灵敏检测双酚A的分析方法。
Abstract：In order to solve the defects of conventional BPA detection methods such as no selectivity, the need for standard samples and complicated pretreatment process, a highly efficient conductive composite film MG@ZIF-7 was synthesized by growing ZIF-7 in situ on the surface of MG with magnetic graphene(MG) as the substrate and ZnO as the Zn source. MG@ZIF-7 was selected as the carrier, endocrine disruptor bisphenol A(BPA) as the template molecule, acryloyl as the functional monomer and divinylbenzene as the cross-linker, and the molecularly imprinted hybrid membrane(MG@ZIF7-MIP) was successfully prepared by surface molecular imprinting technique,which was analytically characterized by TEM, XRD, XPS, FT-IR and other testing methods. And a molecularly imprinted electrochemical sensor with MG@ZIF7-MIP modified electrode as the working electrode was constructed for the selective detection of endocrine disruptor BPA in aqueous environment. The results showed that the linear response range of MG@ZIF7-MIP modified electrode for BPA was 0.001-0.100 μmol/L(R = 0.976 3),the response equilibrium time was 4 min, and the detection limit was 9.84 ng/L(S/N = 3), a rapid response, practical and highly sensitive analytical method for the detection of BPA was developed.
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基本信息:
中图分类号:X832;O657.1;TP212.9
引用信息:
[1]李颖,张永超,霍苗苗,等.MG@ZIF7-MIP的制备及对水环境中双酚A的电化学传感检测[J].天津工业大学学报,2024,43(05):24-30.
基金信息:
国家自然科学基金资助项目（22078246）;; 天津市大学生创新训练计划项目（202110058087）